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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TGFB3
All Species:
35.15
Human Site:
Y100
Identified Species:
85.93
UniProt:
P10600
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P10600
NP_003230.1
412
47328
Y100
Q
E
N
T
E
S
E
Y
Y
A
K
E
I
H
K
Chimpanzee
Pan troglodytes
XP_001161571
412
47357
Y100
Q
E
N
T
E
S
E
Y
Y
A
K
E
I
H
K
Rhesus Macaque
Macaca mulatta
XP_001100053
412
47296
Y100
Q
E
N
T
E
S
E
Y
Y
A
K
E
I
H
K
Dog
Lupus familis
XP_854119
412
47164
Y100
Q
E
N
T
E
S
E
Y
Y
A
K
E
I
H
K
Cat
Felis silvestris
Mouse
Mus musculus
P17125
410
46866
Y98
Q
E
T
S
E
S
E
Y
Y
A
K
E
I
H
K
Rat
Rattus norvegicus
Q07258
412
47097
Y100
Q
E
T
S
E
S
E
Y
Y
A
K
E
I
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506409
334
38141
H101
Q
I
L
R
P
D
E
H
I
A
K
Q
R
Y
I
Chicken
Gallus gallus
P16047
412
47059
Y100
Q
E
N
T
E
S
E
Y
Y
A
K
E
I
H
K
Frog
Xenopus laevis
P17247
413
47621
Y98
R
E
R
S
E
D
E
Y
Y
A
K
E
V
Y
K
Zebra Danio
Brachydanio rerio
NP_919367
410
46964
Y98
Q
D
N
T
E
T
E
Y
Y
A
K
E
I
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97
99.7
98
N.A.
97
97.8
N.A.
71.5
87.3
53.7
73.5
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
97.5
100
99.2
N.A.
98.3
99
N.A.
75.2
93.6
70.6
85.4
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
26.6
100
60
86.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
46.6
100
86.6
100
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
20
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
80
0
0
90
0
100
0
0
0
0
90
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
10
0
0
0
0
0
80
0
% H
% Ile:
0
10
0
0
0
0
0
0
10
0
0
0
80
0
10
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
90
% K
% Leu:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
60
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
90
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
10
0
10
10
0
0
0
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
0
30
0
70
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
20
60
0
10
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
90
0
0
0
0
20
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _